5-CHOLESTEN-3-ALPHA-OL ACETATE → HCID 9846327, compound

Reaction equation

C(O[C@@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3CC[C@@H]2[C@H](C)CCCC(C)C)C1)(=O)C.[O:32]1[C@@H:34]2[CH2:35][C@@H:36]3[C@@H:52]([C@@:53]4([CH3:62])[CH2:54][CH2:55][C@@H:56]([O:58][C:59](=[O:61])[CH3:60])[CH2:57][C@@:33]124)[CH2:51][CH2:50][C@@:49]1([CH3:63])[C@H:37]3[CH2:38][CH2:39][C@@H:40]1[C@H:41]([CH3:48])[CH2:42][CH2:43][CH2:44][CH:45]([CH3:47])[CH3:46]>>[O:32]1[C@@H:34]2[CH2:35][C@@H:36]3[C@@H:52]([C@@:53]4([CH3:62])[CH2:54][CH2:55][C@H:56]([O:58][C:59](=[O:61])[CH3:60])[CH2:57][C@@:33]124)[CH2:51][CH2:50][C@@:49]1([CH3:63])[C@H:37]3[CH2:38][CH2:39][C@@H:40]1[C@H:41]([CH3:48])[CH2:42][CH2:43][CH2:44][CH:45]([CH3:47])[CH3:46]

Participants

Reactant 2

HCID 114303045-CHOLESTEN-3-ALPHA-OL ACETATE

HCID 86587210HCID 86587210, compound

Product 1

HCID 9846327HCID 9846327, compound

Procedure

Following the procedure of Example 3 above, 3α-acetoxycholest-5-ene was epoxidized to 5β,6β-epoxy-3α-acetoxycholestane.

Sources & evidence

ORD record: ord-ec25b767df5146b1a1203cdf22286cb4
Source dataset: uspto-grants-2005_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06841665B2

Reaction notes

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