(4-Benzoylphenyl)(hydroxy)acetonitrile → 2,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid

HRID 1762610

Reaction equation

HRID 1762610 reaction equation
[CH3:1][C:2]1([CH3:16])[CH:4]([CH:5]=[CH:6][C:7]([O:9][CH2:10][CH2:11][CH3:12])=[O:8])[CH:3]1[C:13]([OH:15])=[O:14].C(C(C1C=CC(C(=O)C2C=CC=CC=2)=CC=1)O)#N>>[CH3:16][C:2]1([CH3:1])[CH:4]([CH:5]=[CH:6][C:7]([O:9][CH2:10][CH2:11][CH3:12])=[O:8])[CH:3]1[C:13]([OH:15])=[O:14].[CH3:1][C:2]1([CH3:16])[CH:4]([CH:5]=[CH:6][C:7]([O:9][CH3:10])=[O:8])[CH:3]1[C:13]([O-:15])=[O:14]

Participants

4

Reactant 2

HCID 20041627(4-Benzoylphenyl)(hydroxy)acetonitrileHCID 545705842,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid

Product 2

HCID 545705842,2-Dimethyl-3-(3-propoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acidHCID 86743070HCID 86743070, compound

Procedure

Using the procedure of Example 9, (1R, cis, ΔZ) 2,2-dimethyl-3-(3-methoxy-3-oxo-1-propenyl)-cyclopropane-carboxylic acid and (RS) cyano-(4-benzoyl-phenyl)-methanol were reacted to obtain (RS) cyano (4-benzoyl-phenyl)-methyl (1R, cis, ΔZ) 2,2-dimethyl-3-(3-methoxy-3-oxo-1-propenyl)-cyclopropane-carboxylate.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-9786841e14af4a958fa99474231b3f8c
Source dataset
uspto-grants-1989_05
Patent number
US04833163

Linked notes

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