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Diethylaminoethyl chloride → 3-[4-(2-Diethylaminoethoxy)phenylsulfonyl]-2-(4-tolyl)benzofuran

HRID 1764673
Notes
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Reaction equation

HRID 1764673 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[O:13][C:12]=2[C:20]2[CH:25]=[CH:24][C:23]([CH3:26])=[CH:22][CH:21]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH2:27]([N:29]([CH2:33][CH3:34])[CH2:30][CH2:31]Cl)[CH3:28]>>[CH2:27]([N:29]([CH2:33][CH3:34])[CH2:30][CH2:31][O:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([C:11]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[O:13][C:12]=2[C:20]2[CH:21]=[CH:22][C:23]([CH3:26])=[CH:24][CH:25]=2)(=[O:10])=[O:9])=[CH:6][CH:7]=1)[CH3:28]
ParticipantsProcedureSources & evidenceReaction notes

Participants

3

Reactant 2

HCID 13364Diethylaminoethyl chlorideHCID 227688753-(4-Hydroxyphenylsulfonyl)-2-(4-tolyl)benzofuran

Product 1

HCID 227688853-[4-(2-Diethylaminoethoxy)phenylsulfonyl]-2-(4-tolyl)benzofuran

Procedure

Reaction of 3-(4-hydroxyphenylsulfonyl)-2-(4-tolyl)benzofuran with 2-diethylaminoethyl chloride according to the procedure of Example 1 gives the title compound.

Sources & evidence

ORD record
ord-8b02baadb7d14106aecfabd5d6002046
Source dataset
uspto-grants-1978_09
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US04117128

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes