4-(6-(Bromomethyl)-2-chloropyrido[3,2-D]pyrimidin-4-YL)morpholine → 4-(2-Chloro-6-((3-(4,4-difluoropiperidin-1-yl)azetidin-1-yl)methyl)pyrido[3,2-d]pyrimidin-4-yl)morpholine
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]2[n:7][c:8]([Cl:19])[n:9][c:10]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[c:11]2[n:12]1.[NH:20]1[CH2:21][CH:22]([N:24]2[CH2:25][CH2:26][C:27]([F:30])([F:31])[CH2:28][CH2:29]2)[CH2:23]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]2[n:7][c:8]([Cl:19])[n:9][c:10]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[c:11]2[n:12]1)[N:20]1[CH2:21][CH:22]([N:24]2[CH2:25][CH2:26][C:27]([F:30])([F:31])[CH2:28][CH2:29]2)[CH2:23]1Participants
3
Sources & evidence
- ORD record
- ord-2070a0b0d2154a4fbf4e0c74019ecc10
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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