Benzeneacetamide, N-methoxy- → HCID 10330393, compound
Reaction equation
[CH3:1][O:2][NH:3][C:4](=[O:12])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[Cl:13]OC(C)(C)C>C(Cl)(Cl)Cl>[CH3:1][O:2][N:3]([Cl:13])[C:4](=[O:12])[CH2:5][C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 0 °C
Procedure
Dissolve 1.65 g (10 mmol) of N-(methoxy)-phenylacetamide in 30 cm3 of dry chloroform. Place in an ice-bath and maintain at a temperature of 0° C. Subsequently, pour in progressively, using a flask, 1.30 g (1.36 cm3, 12 mmol) of tert-butyl hypochlorite which has previously been dissolved in 20 cm3 of chloroform.
Workup
- customPlace in an ice-bath
- additionSubsequently, pour in progressively,
Sources & evidence
- ORD record
- ord-34ec70b5e99344f9b8cc44edec933826
- Source dataset
- uspto-grants-1995_01
- Patent number
- US05382593
Reaction notes
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