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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1770039Generated: October 26, 2026

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid → HCID 15231295, compound

https://huagongshe.com/reaction/1770039

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 5210422—
Reactant2-(3-Pyrrolidinyl)-3-pyridinamineHCID 19959014—
ProductHCID 15231295HCID 1523129591%

Reaction Steps

Starting from 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (0.81 g, 3.1 mmol) and 2-(3-pyrrolidinyl)-3-pyridinamine, a procedure analogous to that given in Example 1 provided the title compound (1.15 g, 91%) as an off-white solid, mp >270° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05384407
Source datasetuspto-grants-1995_01
ORD IDord-179ca6247fc34147950a67fdf2286152
Source noteuspto-grants-1995_01