Methanol → 3-{[3-(Aminomethyl)-6-chloro-2-fluorophenyl]oxy}-5-chlorobenzonitrile
Reaction equation
[CH3:34][OH:35].[Cl:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][c:8]([O:10][c:11]2[c:12]([F:30])[c:13]([CH2:18][N:19]3[C:20](=[O:21])[c:22]4[c:23]([cH:24][cH:25][cH:26][cH:27]4)[C:28]3=[O:29])[cH:14][cH:15][c:16]2[Cl:17])[cH:9]1.[NH2:32][NH2:33].[OH2:31]>>[Cl:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][c:8]([O:10][c:11]2[c:12]([F:30])[c:13]([CH2:18][NH2:19])[cH:14][cH:15][c:16]2[Cl:17])[cH:9]1Participants
5
Sources & evidence
- ORD record
- ord-6629be304b1c4daf8d870337062e6006
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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