Reaction equation
[Cl:1][C:2]1[CH:21]=[CH:20][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9]([C:16]([OH:19])(C)[CH3:17])=[N:8]2)=[C:4]([CH3:22])[CH:3]=1.ClC1C=CC(CN2C3C(=CC=CC=3)C(C=O)=N2)=C(C)C=1>>[Cl:1][C:2]1[CH:21]=[CH:20][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9]([CH:16]([OH:19])[CH3:17])=[N:8]2)=[C:4]([CH3:22])[CH:3]=1Participants
3
Procedure
The product was obtained using the method described for the preparation of compound 10b, but using as starting material compound 12a (0.4 mol) instead of compound 10a.
Workup
- customThe product was obtained
Sources & evidence
- ORD record
- ord-b0b8411721cb41eeaee248e4ecef4f21
- Source dataset
- uspto-grants-2016_02
- Patent number
- US09255073B2
Linked notes
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