Acetic Acid → Methyl 2-(isobutylamino)thiophene-3-carboxylate

HRID 177462

Reaction equation

HRID 177462 reaction equation
[C:16]([O:17][BH-:18]([O:19][C:20](=[O:21])[CH3:22])[O:23][C:24](=[O:25])[CH3:26])(=[O:27])[CH3:28].[CH3:33][C:34](=[O:35])[OH:36].[CH:11]([CH:12]([CH3:13])[CH3:14])=[O:15].[Cl:30][CH2:31][Cl:32].[NH2:1][c:2]1[s:3][cH:4][cH:5][c:6]1[C:7](=[O:8])[O:9][CH3:10].[Na+:29]>>[NH:1]([c:2]1[s:3][cH:4][cH:5][c:6]1[C:7](=[O:8])[O:9][CH3:10])[CH2:11][CH:12]([CH3:13])[CH3:14]

Participants

7

Reactant 6

HCID 176Acetic AcidHCID 923Sodium ionHCID 6344DichloromethaneHCID 6561IsobutyraldehydeHCID 78381Methyl 2-amino-3-thenoateHCID 2724942Triacetoxyborohydride

Product 1

HCID 67317044Methyl 2-(isobutylamino)thiophene-3-carboxylate

Sources & evidence

ORD record
ord-da775d3176784f769657e998a966c564
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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