Acetone → Ethyl 2,6-bis(trifluoromethyl)-4-allyloxy-3-pyridinecarboxylate

Reaction equation

[CH2:27]([CH:28]=[CH2:29])[Br:30].[CH3:31][C:32](=[O:33])[CH3:34].[F:1][C:2]([c:3]1[n:4][c:5]([C:15]([F:16])([F:17])[F:18])[cH:6][c:7]([OH:14])[c:8]1[C:9](=[O:10])[O:11][CH2:12][CH3:13])([F:19])[F:20].[K+:21].[K+:22].[O-:23][C:24]([O-:25])=[O:26]>>[F:1][C:2]([c:3]1[n:4][c:5]([C:15]([F:16])([F:17])[F:18])[cH:6][c:7]([O:14][CH2:29][CH:28]=[CH2:27])[c:8]1[C:9](=[O:10])[O:11][CH2:12][CH3:13])([F:19])[F:20]

Participants

Reactant 5

HCID 180Acetone

HCID 813Potassium Cation2×

HCID 7841Allyl bromide

HCID 19660Carbonate Ion

HCID 178470034HCID 178470034, compound

Product 1

HCID 13882865Ethyl 2,6-bis(trifluoromethyl)-4-allyloxy-3-pyridinecarboxylate

Sources & evidence

ORD record: ord-3c0fd5ee6e724ce19fe308cec7f2b7ff
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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