Methanol → [5-(Morpholin-4-ylmethyl)-4,5-dihydro-isoxazol-3-yl]methanol

Reaction equation

[CH3:38][OH:39].[O:1]1[CH2:2][CH2:3][CH2:4][CH2:5][CH:6]1[O:7][CH2:8][C:9]1=[N:10][O:11][CH:12]([CH2:14][N:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[CH2:13]1.[c:21]1([CH3:22])[cH:23][cH:24][c:25]([S:26]([O-:27])(=[O:28])=[O:29])[cH:30][cH:31]1.[nH+:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[OH:7][CH2:8][C:9]1=[N:10][O:11][CH:12]([CH2:14][N:15]2[CH2:16][CH2:17][O:18][CH2:19][CH2:20]2)[CH2:13]1

Participants

Reactant 4

HCID 887Methanol

HCID 85570p-Toluenesulfonate

HCID 4989215Pyridinium

HCID 21978771[5-((Morpholin-4-yl)methyl)-4,5-dihydro-isoxazol-3-yl]methyl 2-tetrahydropyranyl ether

Product 1

HCID 21978759[5-(Morpholin-4-ylmethyl)-4,5-dihydro-isoxazol-3-yl]methanol

Sources & evidence

ORD record: ord-e204a2348f084b4cbe3361cdfab962ee
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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