HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 3,3',5,5'-Tetramethylbenzidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-Bromo-2,6-xylidine | HCID 90549 | — |
| Reactant | Sodium Formate | HCID 2723810 | — |
| Catalyst | Hexadecyltrimethylammonium Bromide | HCID 5974 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3,3',5,5'-Tetramethylbenzidine | HCID 41206 | — |
Reaction Steps
Compound 1a was prepared using the procedure described in P. Bamfield and P. M. Quan, Synthesis, 1978, 537 using 4-bromo-2,6-dimethylaniline (10.00 g, 50 mmol), CTAB (2.00 g, 5.5 mmol, 0.11 eq.), 5% palladium on charcoal (0.80 g, 50% paste), sodium hydroxide (21.1 ml, 8.0M, 0.169 mol) and sodium formate (2×3.40 g, 100 mmol, 2 eq.) in water (30 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07741240B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-cc182d9d04484021af87c82eb45ec3f7 |
| Source note | uspto-grants-2010_06 |