2,4-Dichlorobenzonitrile → (2,4-Dichlorophenyl)(phenyl)methanamine

HRID 1782047

Reaction equation

HRID 1782047 reaction equation

[Cl:1][C:2]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[C:11]1([Mg]Br)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[BH4-].[Na+]>CO>[Cl:1][C:2]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:3]=1[CH:4]([NH2:5])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

5

Reactant 3

HCID 810502,4-Dichlorobenzonitrile

HCID 4311764Sodium borohydride

HCID 178418255HCID 178418255, compound

Product 1

HCID 43184805(2,4-Dichlorophenyl)(phenyl)methanamine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound was prepared from 2,4-dichloro benzonitrile and a) phenyl magnesium bromide b) NaBH4 in MeOH in analogy to known methods.9

Sources & evidence

ORD record: ord-096b44d1e51a4d24bf466367fbbf57f7
Source dataset: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07498339B2

Linked notes

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