Buspirone Hydrochloride → Buspirone

HRID 1783273

Reaction equation

HRID 1783273 reaction equation
Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[N:4][C:3]=1[N:8]1[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][CH2:17][N:18]2[C:27](=[O:28])[CH2:26][C:21]3([CH2:25][CH2:24][CH2:23][CH2:22]3)[CH2:20][C:19]2=[O:29])[CH2:10][CH2:9]1>C(O)C(O)C>[CH:6]1[CH:5]=[N:4][C:3]([N:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][CH2:17][N:18]3[C:27](=[O:28])[CH2:26][C:21]4([CH2:22][CH2:23][CH2:24][CH2:25]4)[CH2:20][C:19]3=[O:29])[CH2:10][CH2:9]2)=[N:2][CH:7]=1

Participants

3

Reactant 1

HCID 36431Buspirone Hydrochloride

Product 1

HCID 2477Buspirone

Reagents, catalysts & solvents 1

HCID 1030Propylene GlycolSolvent

Procedure

A suitable aerosol was generated using buspirone (8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4,5]decane-7,9-dione monohydrochloride) dissolved in propylene glycol (PG).

Sources & evidence

ORD record
ord-83ef781f4c9947aab13f79a839504b63
Source dataset
uspto-grants-2009_03
Patent number
US07501113B2

Linked notes

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