4-Carboxyphenylboronic Acid → HCID 23120528, compound
Reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7](B(O)O)=[CH:6][CH:5]=1)([OH:3])=[O:2].Br[C:14]1[CH:15]=[CH:16][C:17]([CH:20]([F:22])[F:21])=[N:18][CH:19]=1>>[F:21][CH:20]([F:22])[C:17]1[N:18]=[CH:19][C:14]([C:7]2[CH:8]=[CH:9][C:4]([C:1]([OH:3])=[O:2])=[CH:5][CH:6]=2)=[CH:15][CH:16]=1Participants
3
Procedure
Operations similar to those of Production Example 14 were conducted using 4-carboxyphenylboronic acid and 5-bromo-2-(difluoromethyl)pyridine, to provide the title compound as white solid.
Sources & evidence
- ORD record
- ord-813bc511fa8c488fbc2de6d165096ca0
- Source dataset
- uspto-grants-2009_03
- Patent number
- US07504412B2
Reaction notes
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