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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785543Generated: October 27, 2026

5-(4-chlorophenyl)-N-(7-ethoxy-5,8-dihydronaphthalen-1-yl)-1,3-oxazol-2-amine → 8-{[5-(4-pyrrolidin-1-ylphenyl)-1,3-oxazol-2-yl]amino}-3,4-dihydronaphthalen-2(1H)-one

https://huagongshe.com/reaction/1785543

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-chlorophenyl)-N-(7-ethoxy-5,8-dihydronaphthalen-1-yl)-1,3-oxazol-2-amineHCID 67228650—
ReactantN-(7-ethoxy-5,8-dihydronaphthalen-1-yl)-5-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-amineHCID 67229299—
Product8-{[5-(4-pyrrolidin-1-ylphenyl)-1,3-oxazol-2-yl]amino}-3,4-dihydronaphthalen-2(1H)-oneHCID 67229585—

Reaction Steps

The title compound was prepared using the procedure as described in Example 1I, substituting the product of Example 7B for the product of Example 1H.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504520B2
Source datasetuspto-grants-2009_03
ORD IDord-b79294e77d5c4d0e979ae029fe326835
Source noteuspto-grants-2009_03