tert-Butyl piperazine-1-carboxylate → HCID 68563698, compound

HRID 1786480

Reaction equation

HRID 1786480 reaction equation
[CH3:1][CH:2]([N:4]1[CH2:9][CH2:8][CH:7]([O:10][C:11]2[CH:12]=[C:13]3[C:17](=[CH:18][CH:19]=2)[NH:16][C:15]([C:20](O)=[O:21])=[CH:14]3)[CH2:6][CH2:5]1)[CH3:3].[C:23]([O:27][C:28]([N:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1)=[O:29])([CH3:26])([CH3:25])[CH3:24]>>[C:23]([O:27][C:28]([N:30]1[CH2:35][CH2:34][N:33]([C:20]([C:15]2[NH:16][C:17]3[C:13]([CH:14]=2)=[CH:12][C:11]([O:10][CH:7]2[CH2:8][CH2:9][N:4]([CH:2]([CH3:1])[CH3:3])[CH2:5][CH2:6]2)=[CH:19][CH:18]=3)=[O:21])[CH2:32][CH2:31]1)=[O:29])([CH3:26])([CH3:24])[CH3:25]

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 596994565-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid

Product 1

HCID 68563698HCID 68563698, compound

Procedure

The title compound was prepared in analogy to example 40b), from 5-[[1-(1-methylethyl)-4-piperidinyl]oxy]-1H-Indole-2-carboxylic acid and 1-(tert-butoxycarbonyl)piperazine. Light-yellow solid. MS (m/z): 471.1 (M+H)+.

Sources & evidence

ORD record
ord-2328382c02c04eac95bd1adb49588ef6
Source dataset
uspto-grants-2009_03
Patent number
US07507736B2

Linked notes

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