Ferrostatin-1 → HCID 178507370, compound

HRID 1788587

Reaction equation

HRID 1788587 reaction equation
[CH:1]1([NH:7][C:8]2[CH:13]=[CH:12][C:11]([C:14]3[NH:18][N:17]=[N:16][N:15]=3)=[CH:10][C:9]=2[N+:19]([O-])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(OC(=O)C1C=CC(NC2CCCCC2)=C(N)C=1)C>>[CH:1]1([NH:7][C:8]2[C:9]([NH2:19])=[CH:10][C:11]([C:14]3[NH:18][N:17]=[N:16][N:15]=3)=[CH:12][CH:13]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 4068248Ferrostatin-1HCID 178526500HCID 178526500, compound

Product 1

HCID 178507370HCID 178507370, compound

Procedure

The title intermediate was prepared from 1.20 g (4.16 mmol) Compound 128 as described for Compound 11 to yield 0.9 g (83%). MS: 259.18 (M+H+).

Workup

  1. customto yield 0.9 g (83%)

Sources & evidence

ORD record
ord-85c31d8126c4464c93b23e2402334dc3
Source dataset
uspto-grants-2009_03
Patent number
US07511145B2

Linked notes

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