2-Trifluoromethylbenzenesulphonyl chloride → HCID 13934779, compound

HRID 1788909

Reaction equation

HRID 1788909 reaction equation
[Cl:1][C:2]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:13])[C:3]=1[N:14]1[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]1.[F:20][C:21]([F:33])([F:32])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[S:28](Cl)(=[O:30])=[O:29]>>[Cl:1][C:2]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:13])[C:3]=1[N:14]1[CH2:19][CH2:18][N:17]([S:28]([C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=2[C:21]([F:20])([F:32])[F:33])(=[O:30])=[O:29])[CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 1366162-Trifluoromethylbenzenesulphonyl chlorideHCID 6997941,4-Naphthalenedione, 2-chloro-3-(1-piperazinyl)-

Product 1

HCID 13934779HCID 13934779, compound

Procedure

A 1.5 g portion of 3-chloro-2-piperazinyl-1,4-naphthoquinone and 1.26 g of 2-trifluoromethylbenzenesulfonyl chloride were reacted as described in Example 56, giving 1.53 g of the desired product, mp 122°-124° C.

Sources & evidence

ORD record
ord-e28d3533b1644cf894614640d3f6f843
Source dataset
uspto-grants-1987_08
Patent number
US04686220

Linked notes

Loading…