4-(Pyrrolidin-1-yl)butan-1-amine → 5-[1-(4-cyanophenyl)-1H-pyrazol-5-yl]-6-methyl-2-oxo-N-(4-pyrrolidin-1-ylbutyl)-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide

HRID 179680

Reaction equation

HRID 179680 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[n:9]2[n:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][c:16]([C:32]([O:34][CH2:33][CH3:35])=[O:36])[c:17](=[O:31])[n:18](-[c:21]3[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]3)[c:19]2[CH3:20])[cH:7][cH:8]1.[N:37]1([CH2:42][CH2:43][CH2:44][CH2:45][NH2:46])[CH2:38][CH2:39][CH2:40][CH2:41]1>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[n:9]2[n:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][c:16]([C:32](=[O:34])[NH:46][CH2:45][CH2:44][CH2:43][CH2:42][N:37]3[CH2:38][CH2:39][CH2:40][CH2:41]3)[c:17](=[O:31])[n:18](-[c:21]3[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]3)[c:19]2[CH3:20])[cH:7][cH:8]1

Participants

3

Reactant 2

HCID 27627624-(Pyrrolidin-1-yl)butan-1-amineHCID 58218050Ethyl 5-[2-(4-cyanophenyl)-2H-pyrazole-3-yl]-6-methyl-2-oxo-1-(3-trifluoromethylphenyl)-1,2-dihydropyridine-3-carboxylate

Product 1

HCID 670928055-[1-(4-cyanophenyl)-1H-pyrazol-5-yl]-6-methyl-2-oxo-N-(4-pyrrolidin-1-ylbutyl)-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide

Sources & evidence

ORD record
ord-1a2b10ca3b0d4b2a8b0154f1db04ddc0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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