Dichloromethane → 5-[6-[[4-[2-(dimethylamino)ethyl]piperazin-1-yl]methyl]imidazo[4,5-c]pyridin-1-yl]-3-[1-(2-fluorophenyl)ethoxy]thiophene-2-carboxamide

HRID 179869

Reaction equation

HRID 179869 reaction equation
[CH3:1][S:2]([O:3][CH2:6][c:7]1[cH:8][c:9]2[c:10]([cH:11][n:12]1)[n:13][cH:14][n:15]2-[c:16]1[s:17][c:18]([C:31]([NH2:32])=[O:33])[c:19]([O:21][CH:22]([CH3:23])[c:24]2[c:25]([F:30])[cH:26][cH:27][cH:28][cH:29]2)[cH:20]1)(=[O:4])=[O:5].[CH3:34][N:35]([CH2:36][CH2:37][N:38]1[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]1)[CH3:44].[Cl:45][CH2:46][Cl:47]>>[CH2:6]([c:7]1[cH:8][c:9]2[c:10]([cH:11][n:12]1)[n:13][cH:14][n:15]2-[c:16]1[s:17][c:18]([C:31]([NH2:32])=[O:33])[c:19]([O:21][CH:22]([CH3:23])[c:24]2[c:25]([F:30])[cH:26][cH:27][cH:28][cH:29]2)[cH:20]1)[N:41]1[CH2:40][CH2:39][N:38]([CH2:37][CH2:36][N:35]([CH3:34])[CH3:44])[CH2:43][CH2:42]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 27362291-(2-(Dimethylamino)ethyl)piperazineHCID 86647116HCID 86647116, compound

Product 1

HCID 1784669005-[6-[[4-[2-(dimethylamino)ethyl]piperazin-1-yl]methyl]imidazo[4,5-c]pyridin-1-yl]-3-[1-(2-fluorophenyl)ethoxy]thiophene-2-carboxamide

Sources & evidence

ORD record
ord-30c06a0084ab4498a9f709b5e65c8850
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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