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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804151Generated: October 27, 2026

2-Oxazolidinone → 3-{4-[4-(2,4-Dimethylphenyl)piperazine-1-carbonyl]-3-methanesulfonylphenyl}oxazolidin-2-one

https://huagongshe.com/reaction/1804151

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-OxazolidinoneHCID 73949—
Reactant(4-Bromo-2-methanesulfonylphenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanoneHCID 58484856—
Product3-{4-[4-(2,4-Dimethylphenyl)piperazine-1-carbonyl]-3-methanesulfonylphenyl}oxazolidin-2-oneHCID 6738094558.8%

Reaction Steps

By reaction and treatment in the same manner as in Example 1 and using (4-bromo-2-methanesulfonylphenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (451 mg) described in Preparation Example 9 and oxazolidin-2-one (87 mg), the title compound (269 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-8767c08c7440470e82c3ba168b735fac
Source noteuspto-grants-2013_01