Potassium Hydroxide → Potassium 4-hydroxy-2,2-dimethylbutyrate

HRID 1806915Notes

Reaction equation

HRID 1806915 reaction equation
[CH3:1][C:2]1([CH3:8])[CH2:7][CH2:6][O:5][C:3]1=[O:4].[OH-:9].[K+:10]>O>[K+:10].[OH:5][CH2:6][CH2:7][C:2]([CH3:8])([CH3:1])[C:3]([O-:9])=[O:4]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 947462,2-Dimethyl-4-butyrolactone

Product 1

HCID 23712640Potassium 4-hydroxy-2,2-dimethylbutyrateYield 1,783.1%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Step A A mixture of 2,2-dimethylbutyrolactone (6.84 g, 60 mmol) and KOH (3.36 mmol) in H2O (60 mL) was heated at reflux for 2 h. The solution was cooled to room temperature and concentrated to dryness to give 4-hydroxy-2,2-dimethyl-butanoic acid monopotassium salt as a white solid (10.2 g, 100%).

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 2 h
  3. concentrationconcentrated to dryness

Sources & evidence

ORD record
ord-c42223db34144dae94020c94f94a2732
Source dataset
uspto-grants-2013_01
Patent number
US08354444B2

Reaction notes

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