4'-Fluoroformanilide → 2-Chloro-N-(4-fluorophenyl)-9-methyl-9H-purin-6-amine
Reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][CH:9]=O)=[CH:4][CH:3]=1.[Cl:11][C:12]1[N:20]=[C:19]2[C:15]([N:16]=[CH:17][N:18]2[CH3:21])=C(Cl)[N:13]=1>>[Cl:11][C:12]1[N:20]=[C:19]2[C:15]([N:16]=[CH:17][N:18]2[CH3:21])=[C:9]([NH:8][C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)[N:13]=1Participants
3
Procedure
Was prepared according to Example 3 from N-(4-fluoro-phenyl)-formamide and 2,6-dichloro-9-methyl-9H-purine.
Workup
- customWas prepared
Sources & evidence
- ORD record
- ord-4f943904aca545e0881c70fc67bd1418
- Source dataset
- uspto-grants-2013_01
- Patent number
- US08362024B2
Reaction notes
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