Potassium Cation → 3-[2-[4-(1H-indol-3-yl)-1-piperidinyl]ethyl]-2,8-dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one

HRID 181385

Reaction equation

HRID 181385 reaction equation
[CH3:40][CH:41]([CH3:42])[CH2:43][C:44](=[O:45])[CH3:46].[Cl:1][CH2:2][CH2:3][c:4]1[c:5]([CH3:16])[n:6][c:7]2[n:8]([c:9]1=[O:10])[cH:11][cH:12][c:13]([CH3:15])[cH:14]2.[I-:39].[K+:38].[NH:17]1[CH2:18][CH2:19][CH:20]([c:23]2[cH:24][nH:25][c:26]3[cH:27][cH:28][cH:29][cH:30][c:31]23)[CH2:21][CH2:22]1.[Na+:32].[Na+:33].[O-:34][C:35](=[O:36])[O-:37]>>[CH2:2]([CH2:3][c:4]1[c:5]([CH3:16])[n:6][c:7]2[n:8]([c:9]1=[O:10])[cH:11][cH:12][c:13]([CH3:15])[cH:14]2)[N:17]1[CH2:18][CH2:19][CH:20]([c:23]2[cH:24][nH:25][c:26]3[cH:27][cH:28][cH:29][cH:30][c:31]23)[CH2:21][CH2:22]1

Participants

8

Reactant 7

HCID 813Potassium CationHCID 923Sodium ion2×HCID 7909Methyl Isobutyl KetoneHCID 19660Carbonate IonHCID 30165Iodide IonHCID 1008613-(2-chloroethyl)-2,8-dimethyl-4H-pyrido[1,2-a]pyrimidin-4-oneHCID 7022353-(4-Piperidinyl)-1H-indole

Product 1

HCID 205307283-[2-[4-(1H-indol-3-yl)-1-piperidinyl]ethyl]-2,8-dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one

Sources & evidence

ORD record
ord-b8323fd0834a4426812837825c8a8384
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…