Thenyl mercaptan → 4-[[-2-Hydroxy-1-(hydroxymethyl)ethyl]amino]-2-[(2-thienylmethyl)thio]-7(8h)-pteridinone
Reaction equation
F[C:2]1[C:7](F)=[CH:6]C=C[C:3]=1[CH2:9][S:10]([C:13]1[N:22]=[C:21]([NH:23][CH:24]([CH2:27][OH:28])[CH2:25][OH:26])[C:20]2[N:19]=[CH:18][C:17](=[O:29])[NH:16][C:15]=2[N:14]=1)(=O)=O.[S:30]1C=CC=C1CS>>[OH:26][CH2:25][CH:24]([NH:23][C:21]1[C:20]2[N:19]=[CH:18][C:17](=[O:29])[NH:16][C:15]=2[N:14]=[C:13]([S:10][CH2:9][C:3]2[S:30][CH:6]=[CH:7][CH:2]=2)[N:22]=1)[CH2:27][OH:28]Participants
3
Procedure
The titled compound (0.075 g) was prepared by the method of Example 13, step (c) using the product from example 23, step (a) (0.21 g) and 2-thienylmethylmercaptan (0.05 g).
Sources & evidence
- ORD record
- ord-3d6d53405d4e45938237d05d0c8b5a93