N-methyl-2-toluamide → HCID 22503625, compound

HRID 1814513Notes

Reaction equation

HRID 1814513 reaction equation
[CH3:1][NH:2][C:3](=[O:11])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH3:10].[CH2:12]1[CH2:23][O:22][C:21]2[CH:20]=[CH:19][C:16](C#N)=[CH:15][C:14]=2[O:13]1>>[CH2:12]1[CH2:23][O:22][C:21]2[CH:20]=[CH:19][C:16]([C:1]3[NH:2][C:3](=[O:11])[C:4]4[C:5]([CH:10]=3)=[CH:6][CH:7]=[CH:8][CH:9]=4)=[CH:15][C:14]=2[O:13]1

Participants

3

Reactant 2

HCID 75111N-methyl-2-toluamideHCID 28014392,3-Dihydro-1,4-benzodioxine-6-carbonitrile

Product 1

HCID 22503625HCID 22503625, compoundYield 32.2%

Procedure

According to the method of Example 10-1, N-methyl-2-methylbenzamide (5.97 g) and 3,4-ethylenedioxybenzonitrile (6.41 g) were reacted, to give 3-(3,4-ethylenedioxyphenyl)isoquinolin-1-one (3.58 g).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-d6ea71427f6b45c29f0922612587edbe
Source dataset
uspto-grants-2005_04
Patent number
US06875761B2

Reaction notes

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