(R)-7-benzyl-1-(5-hydroxyhexyl)-3-methylxanthine → (S)-1-(5-hydroxyhexyl)-7-methylxanthine
Reaction equation
[OH:1][C@H:2]([CH3:19])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[C:16](=[O:17])[C:15]2[N:14]([CH3:18])[CH:13]=[N:12][C:11]=2[NH:10][C:8]1=[O:9].C(N1C2C(=O)N(CCCC[C@@H](O)C)C(=O)N(C)C=2N=C1)C1C=CC=CC=1.C(N1C2C(=O)N(CCCC[C@H](O)C)C(=O)N(C)C=2N=C1)C1C=CC=CC=1>>[OH:1][C@@H:2]([CH3:19])[CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[C:16](=[O:17])[C:15]2[N:14]([CH3:18])[CH:13]=[N:12][C:11]=2[NH:10][C:8]1=[O:9]Participants
4
Procedure
(S)-1-(5-hydroxyhexyl)-7-methylxanthine was synthesized from (R)-1-(5-hydroxyhexyl)-7-methylxanthine according to the method described in Example 30 for the synthesis of (S)-7-benzyl-1-(5-hydroxyhexyl)-3-methylxanthine from (R)-7-benzyl-1-(5-hydroxyhexyl)-3-methylxanthine.