Ether hydrochloride → (R)-8-hydroxy5-[2-(4,7-Dimethoxy-indan-2-ylamino)-1-hydroxy-ethyl]-1H-quinolin-2-one hydrochloride
Reaction equation
C([O:8][C:9]1[CH:10]=[CH:11][C:12]([C@@H:20]([OH:36])[CH2:21][NH:22][CH:23]2[CH2:31][C:30]3[C:25](=[C:26]([O:34][CH3:35])[CH:27]=[CH:28][C:29]=3[O:32][CH3:33])[CH2:24]2)=[C:13]2[C:18]=1[NH:17][C:16](=[O:19])[CH:15]=[CH:14]2)C1C=CC=CC=1.[ClH:37].C(OCC)C>CO.[Pd]>[ClH:37].[OH:8][C:9]1[CH:10]=[CH:11][C:12]([C@@H:20]([OH:36])[CH2:21][NH:22][CH:23]2[CH2:31][C:30]3[C:25](=[C:26]([O:34][CH3:35])[CH:27]=[CH:28][C:29]=3[O:32][CH3:33])[CH2:24]2)=[C:13]2[C:18]=1[NH:17][C:16](=[O:19])[CH:15]=[CH:14]2Participants
5
