Chlorotrimethylsilane → Silane, trimethyl[[2-methyl-1-(1-methylethyl)-1-propenyl]oxy]-

HRID 1815743

Reaction equation

[CH3:1][CH:2]([C:4](=[O:8])[CH:5]([CH3:7])[CH3:6])[CH3:3].[CH3:9][Si:10](Cl)([CH3:12])[CH3:11]>>[CH3:1][C:2](=[C:4]([O:8][Si:10]([CH3:12])([CH3:11])[CH3:9])[CH:5]([CH3:7])[CH3:6])[CH3:3]

Participants

Reactant 2

HCID 6397Chlorotrimethylsilane

HCID 112712,4-Dimethyl-3-pentanone

Product 1

HCID 11095327Silane, trimethyl[[2-methyl-1-(1-methylethyl)-1-propenyl]oxy]-

Procedure

Reaction between 2,4-dimethyl-3-pentanone (1.2.4.3), trimethylsilyl chloride, and base gave 2,4-dimethyl-3-trimethysilyloxy-2-pentene (1.2.4.4) which was reacted with 1-fluoropyridinium triflate (1.2.4.5) to form 2,4-dimethyl-2-fluoro-3-pentanone (1.2.4.6). This product was reacted with (CH3)3S(O)+I− to form the title compound (1.2.4.2). 1.2.4.7 2,2-Bis-isopropyl oxirane.

Sources & evidence

ORD record: ord-fb2123cb380b4ed4ad0fc92f84e048a2
Source dataset: uspto-grants-2005_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06881732B2

Linked notes

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