Sodium Hydroxide → 439291-60-8
Reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8](C)=[N:7][C:6]=2[CH:11]=1.[OH-].[Na+]>C(O)CO>[F:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:8])=[C:6]([CH:11]=1)[NH2:7]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
5-Fluoro-2-methylbenzothiazole was heated with ethylene glycol and 10N sodium hydroxide solution and the resulting thiol methylated using procedures similar to those described in Example 5, to give 5-fluoro-2-(methylthio)aniline.
Sources & evidence
- ORD record
- ord-4c7d03718dc94128be4bacc7dd1c135c
- Source dataset
- uspto-grants-2005_04
- Patent number
- US06884801B1
Reaction notes
Loading…