2,4-Dichlorobenzyl alcohol → 3-(3-[(2,4-Dichlorobenzyl)oxy]methyl-4-methoxyphenyl)-2-isopropoxypropanoic acid

HRID 1816636Notes

Reaction equation

HRID 1816636 reaction equation
[Cl:1][C:2]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:3]=1[CH2:4][OH:5].Br[CH2:12][C:13]1[CH:14]=[C:15]([CH2:21][CH:22]([O:26][CH:27]([CH3:29])[CH3:28])[C:23]([O-:25])=[O:24])[CH:16]=[CH:17][C:18]=1[O:19][CH3:20]>>[Cl:1][C:2]1[CH:9]=[C:8]([Cl:10])[CH:7]=[CH:6][C:3]=1[CH2:4][O:5][CH2:12][C:13]1[CH:14]=[C:15]([CH2:21][CH:22]([O:26][CH:27]([CH3:29])[CH3:28])[C:23]([OH:25])=[O:24])[CH:16]=[CH:17][C:18]=1[O:19][CH3:20]

Participants

3

Reactant 2

HCID 156842,4-Dichlorobenzyl alcoholHCID 224938933-[3-(Bromomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate

Product 1

HCID 224938753-(3-[(2,4-Dichlorobenzyl)oxy]methyl-4-methoxyphenyl)-2-isopropoxypropanoic acid

Procedure

Using 2,4-dichlorobenzyl alcohol and 3-[3-(bromomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate, 3-(3-[(2,4-dichlorobenzyl)oxy]methyl-4-methoxyphenyl)-2-isopropoxypropanoic acid was obtained in the same method as in Example 247).

Sources & evidence

ORD record
ord-da5796891a12411da25b43e175225225
Source dataset
uspto-grants-2005_04
Patent number
US06884821B1

Reaction notes

Loading…