3-(3-([(Tert-butoxycarbonyl)amino]methyl)-4-methoxyphenyl]-2-isopropoxypropanoate → 3-(3-[(2-Chloro-4-isopropoxybenzoyl)amino]methyl-4-methoxyphenyl)-2-isopropoxypropanoic acid

HRID 1816653

Reaction equation

HRID 1816653 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]([O:11][CH:12]([CH3:14])[CH3:13])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.C(OC([NH:22][CH2:23][C:24]1[CH:25]=[C:26]([CH2:32][CH:33]([O:37][CH:38]([CH3:40])[CH3:39])[C:34]([O-:36])=[O:35])[CH:27]=[CH:28][C:29]=1[O:30][CH3:31])=O)(C)(C)C>>[Cl:1][C:2]1[CH:10]=[C:9]([O:11][CH:12]([CH3:14])[CH3:13])[CH:8]=[CH:7][C:3]=1[C:4]([NH:22][CH2:23][C:24]1[CH:25]=[C:26]([CH2:32][CH:33]([O:37][CH:38]([CH3:40])[CH3:39])[C:34]([OH:36])=[O:35])[CH:27]=[CH:28][C:29]=1[O:30][CH3:31])=[O:6]

Participants

3

Reactant 2

HCID 224939543-(3-([(Tert-butoxycarbonyl)amino]methyl)-4-methoxyphenyl]-2-isopropoxypropanoateHCID 224940892-Chloro-4-isopropoxybenzoic Acid

Product 1

HCID 224942563-(3-[(2-Chloro-4-isopropoxybenzoyl)amino]methyl-4-methoxyphenyl)-2-isopropoxypropanoic acid

Procedure

Using 2-chloro-4-isopropoxybenzoic acid and 3-(3-([(tert-butoxycarbonyl)amino]methyl)-4-methoxyphenyl]-2-isopropoxypropanoate, 3-(3-[(2-chloro-4-isopropoxybenzoyl)amino]methyl-4-methoxyphenyl)-2-isopropoxypropanoic acid was obtained in the same method as in Example 38).

Sources & evidence

ORD record
ord-1b72582df0394b1cb098116d6eb0dd5d
Source dataset
uspto-grants-2005_04
Patent number
US06884821B1

Linked notes

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