Ammonia → 3,3'-Diaminobenzidine

Reaction equation

[C:1]1([C:8]2[CH:14]=[CH:13][C:11]([NH2:12])=[CH:10][CH:9]=2)[CH:7]=[CH:6][C:4]([NH2:5])=[CH:3][CH:2]=1.ClC1C=C(C2C=CC(N)=C(Cl)C=2)C=CC=1[NH2:22].[NH3:31]>[Cu]>[NH2:31][C:10]1[CH:9]=[C:8]([C:1]2[CH:2]=[CH:3][C:4]([NH2:5])=[C:6]([NH2:22])[CH:7]=2)[CH:14]=[CH:13][C:11]=1[NH2:12]

Participants

Procedure

A method according to Patent Document 2 is known as a method directly utilizing a benzidine skeleton. 3,3′-Dichlorobenzidine is treated with ammonia in the presence of a copper catalyst at high temperature (150 to 250° C.) and high pressure (1 to 10 MPa) to yield 3,3′,4,4′-tetraaminobiphenyl (Patent Document 2, Scheme 3).