Alumina → HCID 57892086, compound
Reaction equation
[N+:1]([C:4]1[CH:18]=[CH:17][C:7]2[N:8]=[C:9]([CH2:11][N:12]3[CH2:16][CH2:15][CH2:14][CH2:13]3)[O:10][C:6]=2[CH:5]=1)([O-])=O.[O-2].[Al+3].[O-2].[O-2].[Al+3].ClCCl.C(O)C>CO>[N:12]1([CH2:11][C:9]2[O:10][C:6]3[CH:5]=[C:4]([NH2:1])[CH:18]=[CH:17][C:7]=3[N:8]=2)[CH2:16][CH2:15][CH2:14][CH2:13]1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Prepared analogously to Example VI.1.d from 1.80 g (7.28 mmol) of 6-nitro-2-(pyrrolidin-1-ylmethyl)benzoxazole (VIII.1.b) in methanol as solvent. Yield: 1.10 g (70% of theory); Rf value: 0.60 (aluminum oxide, dichloromethane/ethanol=20:1); C12H15N3O; EII mass spectrum: m/z=218 [M+H]+.
Sources & evidence
- ORD record
- ord-1aa625a669d046d1a2306bdcd6f15e27
- Source dataset
- uspto-grants-2009_10
- Patent number
- US07605176B2
Reaction notes
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