2-Chloropyrimidin-5-amine → N-(2-Chloropyrimidin-5-yl)-5-trifluoromethyl-1-(3-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Reaction equation
[Cl:25][c:26]1[n:27][cH:28][c:29]([NH2:32])[cH:30][n:31]1.[F:1][C:2]([c:3]1[cH:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([CH2:15][c:16]1[cH:17][c:18]([F:22])[cH:19][cH:20][cH:21]1)[c:10]([C:12](=[O:13])[OH:14])[cH:11]2)([F:23])[F:24]>>[F:1][C:2]([c:3]1[cH:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([CH2:15][c:16]1[cH:17][c:18]([F:22])[cH:19][cH:20][cH:21]1)[c:10]([C:12](=[O:13])[NH:32][c:29]1[cH:28][n:27][c:26]([Cl:25])[n:31][cH:30]1)[cH:11]2)([F:23])[F:24]Participants
3
Sources & evidence
- ORD record
- ord-2e98c7acc1114846a872e6fd11c99e1a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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