Ethyl (chloroformyl)acetate → Ethyl 6,8-dichloroimidazo[1,2-b]pyridazine-3-carboxylate

HRID 182292

Reaction equation

HRID 182292 reaction equation
[Br:10][c:11]1[cH:12][c:13]([Cl:14])[n:15][n:16][c:17]1[NH2:18].[Br:19][c:20]1[c:21]2[n:22]([n:23][c:24]([Cl:26])[cH:25]1)[c:27]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[cH:28][n:29]2.[Cl:1][CH:2]([CH:3]=[O:4])[C:5]([O:6][CH2:7][CH3:8])=[O:9]>>[Cl:1][c:20]1[c:21]2[n:22]([n:23][c:24]([Cl:26])[cH:25]1)[c:27]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[cH:28][n:29]2

Participants

4

Reactant 3

HCID 118030Ethyl (chloroformyl)acetateHCID 220244193-Amino-4-bromo-6-chloropyridazineHCID 59313730Ethyl 8-bromo-6-chloroimidazo[1,2-b]pyridazine-3-carboxylate

Product 1

HCID 59314032Ethyl 6,8-dichloroimidazo[1,2-b]pyridazine-3-carboxylate

Sources & evidence

ORD record
ord-a0473eb61a2a423689bf5db507e14675
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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