P-Anisidine → HCID 178492222, compound
Reaction equation
[NH2:1][C:2]1[CH2:6][C:5](=[O:7])[NH:4][N:3]=1.[CH3:8][O:9][C:10]1[CH:16]=[CH:15][C:13](N)=[CH:12][CH:11]=1>C(O)(=O)C>[CH3:8][O:9][C:10]1[CH:16]=[CH:15][C:13]([NH:1][C:2]2[CH2:6][C:5](=[O:7])[NH:4][N:3]=2)=[CH:12][CH:11]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 3-amino-2-pyrazolin-5-one (20 mmol), 4-methoxyaniline (25 mol) in 50 ml of acetic acid was refluxed for 4 hours. The solvent was evaporated, the residue was suspended in water. The solid was filtered and crystallized from methanol.
Workup
- temperaturewas refluxed for 4 hours
- customThe solvent was evaporated
- filtrationThe solid was filtered
- customcrystallized from methanol
Sources & evidence
- ORD record
- ord-37d20950e35341e88033d86044f315ff
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07060822B1
Reaction notes
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