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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 18300Generated: October 27, 2026

Ethyl indole-2-carboxylate → methyl 1-methyl-1H-indole-7-carboxylate

https://huagongshe.com/reaction/18300

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl indole-2-carboxylateHCID 73125—
ReactantMethyl indole-7-carboxylateHCID 676694—
Productmethyl 1-methyl-1H-indole-7-carboxylateHCID 1082147890%

Reaction Steps

According to the procedure of Preparation 9 (a), except substituting methyl indole-7-carboxylate for the ethyl indole-2-carboxylate, the title compound (2.4 g, 90%) was obtained as an oil: MS (ES) m/e 190.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07741339B2
Source datasetuspto-grants-2010_06
ORD IDord-ec600b9a03df41abab030bf8e0e763b6
Source noteuspto-grants-2010_06