5-Bromo-N-ethylpyridine-3-carboxamide → HCID 22049754, compound
Reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:12]=1)[C:7]([NH:9][CH2:10][CH3:11])=[O:8].[Cu](C#N)[C:14]#[N:15]>>[C:14]([C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:12]=1)[C:7]([NH:9][CH2:10][CH3:11])=[O:8])#[N:15]Participants
3
Procedure
By the reaction in the same manner as in Example 42-ii) using 5-bromo-N-ethylnicotinamide (580 mg) and copper cyanide (350 mg), the title compound (141 mg) was obtained as colorless powder crystals.
Workup
- customBy the reaction in the same manner as in Example 42-ii)
Sources & evidence
- ORD record
- ord-efbc557ad97b47129fa512d6b680741a
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07067537B2
Reaction notes
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