2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → N-[3-(1-{[2-(Isopentyloxy)-1-naphthyl]methyl}-4-piperidinyl)phenyl]-2-methylpropanamide

HRID 1832335

Reaction equation

HRID 1832335 reaction equation
[CH2:1]([O:6][C:7]1[CH:16]=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]=1[CH:17]=O)[CH2:2][CH:3]([CH3:5])[CH3:4].[CH3:19][CH:20]([CH3:36])[C:21]([NH:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:25]=1)=[O:22]>>[CH2:1]([O:6][C:7]1[CH:16]=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]=1[CH2:17][N:33]1[CH2:34][CH2:35][CH:30]([C:26]2[CH:25]=[C:24]([NH:23][C:21](=[O:22])[CH:20]([CH3:19])[CH3:36])[CH:29]=[CH:28][CH:27]=2)[CH2:31][CH2:32]1)[CH2:2][CH:3]([CH3:4])[CH3:5]

Participants

3

Reactant 2

HCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 220486042-(Isopentyloxy)-1-naphthaldehyde

Product 1

HCID 22048987N-[3-(1-{[2-(Isopentyloxy)-1-naphthyl]methyl}-4-piperidinyl)phenyl]-2-methylpropanamide

Procedure

Prepared by Procedure F and Scheme R using 2-(isopentyloxy)-1-naphthaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 473.3 (M+H)+.

Workup

  1. customPrepared by Procedure F and Scheme R

Sources & evidence

ORD record
ord-d87044527f6b4248acc5b19b937fb5fe
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Linked notes

Loading…