4-(1,2,3-Thiadiazol-4-yl)benzaldehyde → 2-Methyl-N-(3-{1-[4-(1,2,3-thiadiazol-4-YL)benzyl]-4-piperidinyl}phenyl)propanamide

HRID 1832414

Reaction equation

HRID 1832414 reaction equation
[S:1]1[CH:5]=[C:4]([C:6]2[CH:13]=[CH:12][C:9]([CH:10]=O)=[CH:8][CH:7]=2)[N:3]=[N:2]1.[CH3:14][CH:15]([CH3:31])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[CH:20]=1)=[O:17]>>[CH3:14][CH:15]([CH3:31])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH:25]2[CH2:30][CH2:29][N:28]([CH2:10][C:9]3[CH:12]=[CH:13][C:6]([C:4]4[N:3]=[N:2][S:1][CH:5]=4)=[CH:7][CH:8]=3)[CH2:27][CH2:26]2)[CH:20]=1)=[O:17]

Participants

3

Reactant 2

HCID 27764534-(1,2,3-Thiadiazol-4-yl)benzaldehydeHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 220490412-Methyl-N-(3-{1-[4-(1,2,3-thiadiazol-4-YL)benzyl]-4-piperidinyl}phenyl)propanamide

Procedure

Prepared by Procedure F and Scheme R using 4-(1,2,3-thiadiazol-4-yl)benzaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 421.1 (M+H)+.

Workup

  1. customPrepared by Procedure F and Scheme R

Sources & evidence

ORD record
ord-7af2fe8d59cd41538dd244456d527465
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Linked notes

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