5-Chloro-1-pentanol → N-{3-[1-(5-Hydroxypentyl)-4-piperidinyl]phenyl}-2-methylpropanamide

HRID 1832440

Reaction equation

HRID 1832440 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][OH:7].[CH3:8][CH:9]([CH3:25])[C:10]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([CH:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)[CH:14]=1)=[O:11]>>[OH:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][N:22]1[CH2:23][CH2:24][CH:19]([C:15]2[CH:14]=[C:13]([NH:12][C:10](=[O:11])[CH:9]([CH3:8])[CH3:25])[CH:18]=[CH:17][CH:16]=2)[CH2:20][CH2:21]1

Participants

3

Reactant 2

HCID 789155-Chloro-1-pentanolHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 22049029N-{3-[1-(5-Hydroxypentyl)-4-piperidinyl]phenyl}-2-methylpropanamide

Procedure

Prepared by Procedure G and Scheme B1 using 5-chloro-1-pentanol and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 333.3 (M+H)+.

Workup

  1. customPrepared by Procedure G and Scheme B1

Sources & evidence

ORD record
ord-87fd57aabd8347f2aad6902e4da0778c
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Linked notes

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