4-bromo-2,3-dihydro-1H-indol-2-one → 2-[(4-bromo-2-oxo-1H-indol-3-ylidene)methyl]-5-(2-hydroxy-3-morpholin-4-ylpropyl)-3-methyl-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4-one

HRID 183554

Reaction equation

HRID 183554 reaction equation
[Br:24][c:25]1[c:26]2[c:30]([cH:31][cH:32][cH:33]1)[NH:29][C:28](=[O:34])[CH2:27]2.[OH:1][CH:2]([CH2:3][N:4]1[C:5](=[O:16])[c:6]2[c:7]([nH:10][c:11]([CH:14]=[O:15])[c:12]2[CH3:13])[CH2:8][CH2:9]1)[CH2:17][N:18]1[CH2:19][CH2:20][O:21][CH2:22][CH2:23]1>>[OH:1][CH:2]([CH2:3][N:4]1[C:5](=[O:16])[c:6]2[c:7]([nH:10][c:11]([CH:14]=[C:27]3[c:26]4[c:25]([Br:24])[cH:33][cH:32][cH:31][c:30]4[NH:29][C:28]3=[O:34])[c:12]2[CH3:13])[CH2:8][CH2:9]1)[CH2:17][N:18]1[CH2:19][CH2:20][O:21][CH2:22][CH2:23]1

Participants

3

Reactant 2

HCID 27631904-bromo-2,3-dihydro-1H-indol-2-oneHCID 593759885-(2-hydroxy-3-morpholin-4-ylpropyl)-3-methyl-4-oxo-6,7-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde

Product 1

HCID 675320762-[(4-bromo-2-oxo-1H-indol-3-ylidene)methyl]-5-(2-hydroxy-3-morpholin-4-ylpropyl)-3-methyl-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4-one

Sources & evidence

ORD record
ord-b0be890d500b4dccb775d88bfeeaf4a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…