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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 184439Generated: October 26, 2026

Hydrochloric Acid → 4-(benzenesulfonyl)-N-(cyanomethyl)-1-(2,2,2-trifluoro-1-phenylethyl)pyrrolidine-2-carboxamide

https://huagongshe.com/reaction/184439

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantTrifluoromethanesulfonic anhydrideHCID 67749—
ReactantDiisopropylethylamineHCID 81531—
Reactant(S)-alpha-(Trifluoromethyl)benzyl alcoholHCID 95556—
Reactant4-(benzenesulfonyl)-N-(cyanomethyl)pyrrolidine-2-carboxamideHCID 142711121—
Product4-(benzenesulfonyl)-N-(cyanomethyl)-1-(2,2,2-trifluoro-1-phenylethyl)pyrrolidine-2-carboxamideHCID 75246253—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-4f3cc686d02f46c291d236219fa5fe63
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)