1,4-Benzodioxan-6-ylamine → HCID 86689321, compound
Reaction equation
O([C:9]1[CH:18]=[CH:17][C:16]2[CH2:15][CH2:14][CH2:13][CH2:12][C:11]=2[C:10]=1[N+:19]([O-:21])=[O:20])S(C(F)(F)F)(=O)=O.[NH2:22][C:23]1[CH:32]=[CH:31][C:26]2[O:27][CH2:28][CH2:29][O:30][C:25]=2[CH:24]=1>>[N+:19]([C:10]1[C:11]2[CH2:12][CH2:13][CH2:14][CH2:15][C:16]=2[CH:17]=[CH:18][C:9]=1[NH:22][C:23]1[CH:32]=[CH:31][C:26]2[O:27][CH2:28][CH2:29][O:30][C:25]=2[CH:24]=1)([O-:21])=[O:20]Participants
3
Procedure
1-Nitro-5,6,7,8-tetrahydronaphthalen-2-yl triflate (3.25 g, 10 mmol) and 6-amino-2,3-dihydrobenzo[1,4]dioxin (1.51 g, 10 mmol) were used in a process similar to Example 1(1) to give the titled compound as red oil (3.20 g, yield 98%).
Sources & evidence
- ORD record
- ord-49b9c37b0a6d42f2807198f5ba04551a
- Source dataset
- uspto-grants-2015_02
- Patent number
- US08962613B2