Thionyl Chloride → 3-(1-Adamantyl)propanoyl chloride
Reaction equation
[C:1]12([CH2:11][CH2:12][C:13]([OH:15])=O)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.S(Cl)([Cl:18])=O>>[C:1]12([CH2:11][CH2:12][C:13]([Cl:18])=[O:15])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2Participants
3
Procedure
3-(1-Adamantyl)propanic acid was reacted with thionyl chloride as describe in Example 10A to provide the title compound as colorless oil.
Sources & evidence
- ORD record
- ord-727f89c4cf0049f498f9646e85fd5046
- Source dataset
- uspto-grants-2015_02
- Patent number
- US08962639B2
Reaction notes
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