Ethyl 5-amino-1-(2-fluorophenyl)-1H-pyrazole-3-carboxylate → HCID 68202333, compound
Reaction equation
[O:1]=[S:2]1(=[O:21])[CH2:6][CH2:5][CH2:4][N:3]1[C:7]1[N:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[N:10]=[C:9]([C:18]([OH:20])=[O:19])[CH:8]=1.C(OC(C1C=C(N)N(C2C=CC=CC=2[F:39])N=1)=O)C>>[O:21]=[S:2]1(=[O:1])[CH2:6][CH2:5][CH2:4][N:3]1[C:7]1[N:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[F:39])[N:10]=[C:9]([C:18]([OH:20])=[O:19])[CH:8]=1Participants
3
Procedure
According to this procedure 5-(1,1-Dioxo-1lambda*6*-isothiazolidin-2-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid is prepared starting from 5-Amino-1-(2-fluoro-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester.
Workup
- customis prepared
Sources & evidence
- ORD record
- ord-8b590ec9951d469fbe1c69b57b5078e2
- Source dataset
- uspto-grants-2015_02