Methyl iodide → HCID 135617937, compound

Reaction equation

[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([CH2:6][C:7]2[C:8](=[O:15])[NH:9][C:10](=[S:14])[NH:11][C:12]=2[CH3:13])=[CH:4][CH:3]=1.[CH3:18]I>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][C:7]2[C:8](=[O:15])[NH:9][C:10]([S:14][CH3:18])=[N:11][C:12]=2[CH3:13])=[CH:16][CH:17]=1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 27721345-((4-Chlorophenyl)methyl)-2,3-dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone

Product 1

HCID 135617937HCID 135617937, compound

Procedure

5-(4-Chlorobenzyl)-6-methyl-2-thiouracil was methylated with methyl iodide as described in Example 1(i) to give 5-(4-chlorobenzyl)-6-methyl-2-methylthio-4-pyrimidone (m.p. 248°-251°).

Sources & evidence

ORD record: ord-3fcae2403e2147358e3cb9d4834e86af
Source dataset: uspto-grants-1980_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04218452

Reaction notes

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