HCID 178432734, compound → HCID 178432742, compound

Reaction equation

I[C:2]1[NH:6][C:5]([CH3:7])=[N:4][C:3]=1[CH:8]([CH3:10])[CH3:9].ClC1C=C(SC2NC(C)=NC=2C(C)C)C=C(Cl)C=1>>[CH:8]([C:3]1[N:4]=[C:5]([CH3:7])[NH:6][CH:2]=1)([CH3:10])[CH3:9]

Participants

Reactant 2

HCID 178432734HCID 178432734, compound

HCID 178432748HCID 178432748, compound

Product 1

HCID 178432742HCID 178432742, compound

Procedure

4-Isopropyl-2-methylimidazole (3a) was synthesized in accordance with the procedure described in EP-A 585014, while 5-iodo-4-isopropyl-2-methylimidazole (4a) and 5-(3,5-dichlorophenylthio)-4-isopropyl-2-methyl-1H-imidazole (5a) were synthesized in accordance with the procedure described in Japanese Kokai Hei-5-255270.

Workup

customwere synthesized in accordance with the procedure

Sources & evidence

ORD record: ord-22ab9855d396441a9048080b4dfbc1e3
Source dataset: uspto-grants-2000_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06147097

Reaction notes

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